Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
BCN-exo-PEG3-NH2 is a BCN-functionalized PEG3 amine linker used in bioorthogonal conjugation and PROTAC linker synthesis. It provides a strained alkyne handle and a terminal primary amine to enable modular coupling strategies, and is commonly supplied in research-scale quantities at high reported purity.
Provides a strained alkyne (BCN) for rapid bioorthogonal click reactions.
Contains a PEG3 spacer for flexibility and improved solubility.
Features a terminal primary amine for amide or reductive amination conjugation.
Suitable for linker construction in targeted degradation and bioconjugation workflows.
Supplied in research-scale quantities with supplier-reported high purity.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DBCO-PEG3-VC-Exatecan is a drug-linker conjugate used in antibody-drug conjugate (ADC) research that couples a DBCO-functionalized PEG3 valine-citrulline cleavable linker to the topoisomerase I inhibitor exatecan.
Provides a cleavable valine-citrulline (VC) linker for intracellular release.
Includes a DBCO handle for strain-promoted azide-alkyne cycloaddition (click chemistry).
Incorporates a PEG3 spacer to improve solubility and linker flexibility.
Delivers exatecan, a DNA topoisomerase I inhibitor payload.
High purity (~96.7%) and large molecular weight (~1331.44 g/mol).
Soluble in DMSO at 50 mg/mL with ultrasonic assistance.
Stored sealed at -20 °C; in solution, stable at -80 °C for 6 months and -20 °C for 1 month.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
m-PEG5-Br is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It facilitates the degradation of target proteins by exploiting the intracellular ubiquitin-proteasome system.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Exploits ubiquitin-proteasome system
Selectively degrades target proteins
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that is utilized in the synthesis of PROTACs. PROTACs themselves are small molecules composed of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
Application: used in the synthesis of PROTACs.
Mechanism: facilitates the degradation of target proteins via the ubiquitin-proteasome system when incorporated into PROTACs.
Research use: for research purposes only; not intended for sale to patients.
Form: liquid (density: 1.252 g/cm3), colorless to light yellow.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2 3 5 6-Di-O-isopropylidene- -D-mannofuranose is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other to the target protein. These molecules function by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
For research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More